22nd Century Group Inc is a United States-based biotechnology company focused on utilizing alkaloid plant technologies to improve health and wellness with reduced nicotine tobacco, and hemp/cannabis. It has two operating segments; The tobacco segment is engaged in commercializing its proprietary VLNC tobacco plants and cigarette products, which contain 95% less nicotine than conventional tobacco and cigarettes, and research cigarettes sold under the brand name SPECTRUM, and The hemp/cannabis segment is engaged in providing hemp-derived cannabinoid ingredients and API, as well as a CDMO to the consumer goods industry. It derives a majority of its revenue from the tobacco segment.